By Allan H. Ropper, Robert H. Brown

ISBN-10: 007141620X

ISBN-13: 9780071416207

A new tackle the vintage, definitive textual content at the complete spectrum of neurology. Reflecting a contemporary method of neurology, Adams and Victor�s rules of Neurology, 8/e new layout highlights a extra entire and obtainable techniques to therapy and scientific administration innovations. This completely revised variation positive aspects extra assurance of remedy and neuroimaging, renown symptoms sections built-in all through, and over 800 illustrations.

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Extra info for Adams and Victor's Principles of Neurology (8th Edition)

Sample text

A compressive lesion of an optic nerve will have the same effect as a demyelinative one. Many other diseases of the optic nerves— including toxic and nutritional amblyopias, ischemic optic neuropathy, and the Leber type of hereditary optic neuropathy— show abnormalities of the PSVER. Glaucoma and other diseases involving structures anterior to the retinal ganglion cells may also produce increased latencies. Impaired visual acuity has little effect on the latency but does correlate well with the amplitude of the PSVER (a property that is exploited in computerized testing for visual acuity).

The term alpha coma refers to a unique EEG pattern in which an apparent alpha activity in the 8- to 12-Hz range is distributed widely over the hemispheres rather than in its normal location posteriorly. When analyzed carefully, this apparent alpha activity, unlike the normal monorhythmic alpha, is found to vary slightly in frequency within in a narrow band. This is usually a transitional pattern after global anoxia; less often, alpha coma is seen with large acute pontine lesions. With severe hypothyroidism, the brain waves are normal in configuration but usually of decreased frequency.

The electroencephalograph records spontaneous electrical ac- 24 PART 1 THE CLINICAL METHOD OF NEUROLOGY tivity generated in the cerebral cortex. This activity reflects the electrical currents that flow in the extracellular spaces of the brain, and these reflect the summated effects of innumerable excitatory and inhibitory synaptic potentials upon cortical neurons. This spontaneous activity of cortical neurons is much influenced and synchronized by subcortical structures, particularly the thalamus and high brainstem reticular formation.

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Adams and Victor's Principles of Neurology (8th Edition) by Allan H. Ropper, Robert H. Brown


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